Amb929 - CAS 438196-25-9

Amb929 (ZINC000002782982), an nsp3 ligand, is a drug active against SARS-CoV-2. It inhibits the replication of SARS-CoV-2-mNG in VeroE6 cells with an EC50 value of 34.7 μM. Amb929 exhibits limited to moderate cytotoxicity in VeroE6 cells (CC50: 281 μM) and also suppresses the replication of SARS-CoV-2-mNG in human airway epithelium (HAE) .

SARS-CoV

Microbiology/Virology

438162

C29H27N3O4S

513.61

O=C(OC)C1=CC=C(C=C1)NC(=S)NC(=O)C2=CC(=NC=3C=CC=CC32)C=4C=CC=C(OCC(C)C)C4

-20°C

Ice Packs

Small Compound