Ambroxol/acefylline - CAS 96989-76-3

Ambroxol/acefylline, an active metabolite of the proagent Bromhexine, has potent expectorant effects and functions as a glucocerebrosidase (GCase) chaperone, increasing GCase activity. It induces lung autophagy and has potential applications in Parkinson's disease and neuronopathic Gaucher disease research [1][2].

Autophagy, Glucosidase, glycosidase

Autophagy, Metabolism

96989-76-3

C22H28Br2N6O5

616.3

C(C(O)=O)N1C2=C(N(C)C(=O)N(C)C2=O)N=C1.C(N[C@H]1CC[C@H](O)CC1)C2=C(N)C(Br)=CC(Br)=C2

-20°C

Ice Packs

Small Compound