AMG-315 - CAS 2244425-65-6

AMG-315 is a Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes. AMG-315 is a chiral arachidonoyl ethanolamide (AEA) analogue or (13S,1′R) -dimethylanandamide. AMG-315 is a high affinity ligand for the CB1 receptor (Ki of 7.8 ± 1.4 nM) that behaves as a potent CB1 agonist in vitro (EC50 = 0.6 ± 0.2 nM) . AMG-315 is the first potent AEA analogue with significant stability for all endocannabinoid hydrolyzing enzymes as well as the oxidative enzymes COX-2. AMG-315 will serve as a very useful endocannabinoid probe.

Others

Others

2244354

C24H41NO2

375.59

C(CC/C=C\C/C=C\C/C=C\[C@H](/C=C\CCCCC)C)C(N[C@@H](CO)C)=O

-20°C

Ice Packs

Small Compound