Molfinity

AMG-458 - CAS 913376-83-7

SKU:MF-0049772-01

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Product Details

Bioactivity
AMG-458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met than VEGFR2 in cells.
Target
C-Met/HGFR
Related Pathways
Tyrosine Kinase/Adaptors
CAS Number
913286
Purity
0.9998
Molecular Formula
C30H29N5O5
Molecular Weight
539.58
SMILES
COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(CC(C)(C)O)n(-c5ccccc5)c4=O)nc3)ccnc2c1
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound