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Molfinity

AMG-47a - CAS 882663-88-9

AMG-47a - CAS 882663-88-9

MF-0062706-01

$38.41 USD
$38.41 USD
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Product Details

  • Bioactivity

    AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells.

  • Target

    Kras, Ras, JAK, VEGFR, p38 MAPK, Src

  • Related Pathways

    Chromatin/Epigenetic, MAPK, Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling, Stem Cells

  • CAS Number

    882566

  • Purity

    0.98069

  • Molecular Formula

    C29H28F3N5O2

  • Molecular Weight

    535.56

  • SMILES

    Cc1ccc(cc1-c1ccc2nc(NCCN3CCOCC3)ncc2c1)C(=O)Nc1cccc(c1)C(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound