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Molfinity

AMG 487 - CAS 473719-41-4

AMG 487 - CAS 473719-41-4

MF-0004377-01

$44.38 USD
$44.38 USD
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Product Details

  • Bioactivity

    AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively.

  • Target

    CXCR

  • Related Pathways

    GPCR/G Protein, Autophagy, Immunology/Inflammation

  • CAS Number

    473674

  • Purity

    0.9989

  • Molecular Formula

    C32H28F3N5O4

  • Molecular Weight

    603.59

  • SMILES

    CCOc1ccc(cc1)-n1c(nc2ncccc2c1=O)[C@@H](C)N(Cc1cccnc1)C(=O)Cc1ccc(OC(F)(F)F)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound