Molfinity

AMG 517 - CAS 659730-32-2

SKU:MF-0018873-01

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Size 2 mg 5 mg 1 mL - 10 mM (in DMSO) 10 mg 25 mg 50 mg 100 mg

Product Details

Bioactivity
AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM), and heat activation (IC50: 1.3 nM) of TRPV1.
Target
TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel
CAS Number
659696
Purity
0.9985
Molecular Formula
C20H13F3N4O2S
Molecular Weight
430.4
SMILES
O(C1=C2C(SC(NC(C)=O)=N2)=CC=C1)C=3C=C(N=CN3)C4=CC=C(C(F)(F)F)C=C4
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound