AMG 837 calcium hydrate - CAS 1259389-38-2

AMG 837 calcium hydrate, a potent GPR40 agonist with an EC50 of 13 nM, exhibits high selectivity over GPR41, GPR43, and GPR120 (EC50 > 10,000 nM) .

GPCR

GPCR/G Protein, Endocrinology/Hormones

1259349

0.9896

C52H44CaF6O8

950.97

[H]O[H].[H]O[H].O=C([O-])C[C@H](C#CC)C1=CC=C(OCC2=CC(C3=CC=C(C(F)(F)F)C=C3)=CC=C2)C=C1.O=C([O-])C[C@H](C#CC)C4=CC=C(OCC5=CC(C6=CC=C(C(F)(F)F)C=C6)=CC=C5)C=C4.[Ca+2]

-20°C

Ice Packs

Small Compound