AMG 837 hemicalcium - CAS 1291087-14-3

AMG 837 hemicalcium is a potent, orally active GPR40/FFA1 partial agonist that inhibits the specific binding of [3H]AMG 837 to the human FFA1 receptor (pIC50: 8.13) . It promotes insulin secretion and reduces glucose levels in rodents.

Others, GPCR

Endocrinology/Hormones, GPCR/G Protein, Others

1291087-14-3

C52H40CaF6O6

914.954

CC#C[C@@H](CC(=O)[O-])C1=CC=C(C=C1)OCC2=CC(=CC=C2)C3=CC=C(C=C3)C(F)(F)F.CC#C[C@@H](CC(=O)[O-])C1=CC=C(C=C1)OCC2=CC(=CC=C2)C3=CC=C(C=C3)C(F)(F)F.[Ca+2]

-20°C

Ice Packs

Small Compound