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Molfinity

AMG-8718 - CAS 1215868-94-2

AMG-8718 - CAS 1215868-94-2

MF-0043663-01

$1,927.85 USD
$1,927.85 USD
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Product Details

  • Bioactivity

    AMG-8718 is a selective, orally active and potent BACE1 inhibitor that acts on both BACE1 (IC50: 0.0007 μM) and BACE2 (IC50: 0.005 μM) . AMG-8718 significantly reduces CSF and Aβ40 levels in the brain.

  • Target

    Beta-Secretase, Others

  • Related Pathways

    Others, Neuroscience

  • CAS Number

    1215772

  • Molecular Formula

    C25H19FN4O3

  • Molecular Weight

    442.44

  • SMILES

    NC1=N[C@]2(C=3C(OC=4C2=CC(C#CC5(C)COC5)=CN4)=CC=C(C3)C6=C(F)N=CC=C6)CO1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound