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Molfinity

AMG 900 - CAS 945595-80-2

AMG 900 - CAS 945595-80-2

MF-0062687-01

$42.89 USD
$42.89 USD
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Product Details

  • Bioactivity

    AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 values of 5 nM, 4 nM, and 1 nM, respectively. It exhibits over 10-fold selectivity for Aurora kinases compared to p38α, Tyk2, JNK2, Met, and Tie2. [Phase 1].

  • Target

    P38 MAPK, Aurora Kinase, Tyrosine Kinases

  • Related Pathways

    Chromatin/Epigenetic, Cell Cycle/Checkpoint, MAPK, Tyrosine Kinase/Adaptors

  • CAS Number

    945513

  • Purity

    0.9951

  • Molecular Formula

    C28H21N7OS

  • Molecular Weight

    503.58

  • SMILES

    Cc1csc(c1)-c1nnc(Nc2ccc(Oc3ncccc3-c3ccnc(N)n3)cc2)c2ccccc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound