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AMG PERK 44 - CAS 1883548-84-2

AMG PERK 44 - CAS 1883548-84-2

MF-0004380-01

$58.59 USD
$58.59 USD
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Product Details

  • Bioactivity

    AMG PERK 44 is an orally active and selective PERK inhibitor (IC50: 6 nM) that induces autophagy. It also inhibits GCN2 (IC50: 7300 nM) and B-Raf (IC50 >1000 nM), making it useful for cancer research.

  • Target

    PERK, Autophagy

  • Related Pathways

    Apoptosis, Autophagy

  • CAS Number

    1883462

  • Purity

    0.9981

  • Molecular Formula

    C34H29ClN4O2

  • Molecular Weight

    561.07

  • SMILES

    Cl.Cc1ccc2cc(ccc2n1)-c1c(C)ccc(C(=O)c2c(-c3ccccc3)n(C)n(-c3ccccc3)c2=O)c1N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound