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Molfinity

AMG28 - CAS 1202764-07-5

AMG28 - CAS 1202764-07-5

MF-0062725-01

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Product Details

  • Bioactivity

    AMG28 is an inhibitor of Tau tubulin kinase 1 (TTBK1) and TTBK2, with IC50 values of 805 nM and 988 nM, respectively. Additionally, AMG28 suppresses the phosphorylation of tau protein at the Ser422 site, with an IC50 of 1.85 μM.

  • Target

    Microtubule Associated

  • Related Pathways

    Cytoskeletal Signaling

  • CAS Number

    1202764-07-5

  • Molecular Formula

    C20H20N4O

  • Molecular Weight

    332.399

  • SMILES

    OC(C#CC=1C=CC=2NC3=C(C=4N=C(N=CC4CCC3)N)C2C1)(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound