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Molfinity

AMI-1 free acid - CAS 134-47-4

AMI-1 free acid - CAS 134-47-4

SKU:MF-0009402-01

Regular price $31.68 USD
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  • Bioactivity

    AMI-1 free acid is a potent, cell-permeable, and reversible inhibitor of protein arginine N-methyltransferases (PRMTs), with inhibitory concentration 50 (IC50) values of 8.8 μM for human PRMT1 and 3.0 μM for yeast-Hmt1p. It achieves its PRMTs inhibitory activity by obstructing peptide-substrate binding [1].

  • Target

    Histone Methyltransferase

  • Related Pathways

    Chromatin/Epigenetic

  • CAS Number

    83

  • Purity

    0.978

  • Molecular Formula

    C21H16N2O9S2

  • Molecular Weight

    504.49

  • SMILES

    O=C(NC=1C=CC2=C(O)C=C(C=C2C1)S(=O)(=O)O)NC=3C=CC4=C(O)C=C(C=C4C3)S(=O)(=O)O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound