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Aminopeptidase N Inhibitor - CAS 596108-59-7

Aminopeptidase N Inhibitor - CAS 596108-59-7

SKU:MF-0052683-01

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  • Bioactivity

    Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 μM) . It is selective for AP-N/CD13 over matrix metalloproteinase-9 (MMP-9), angiotensin converting enzyme (ACE), neutral endopeptidase (NEP), γ-glutamyl transpeptidase, and the serine proteases dipeptidyl peptidase 4 (DPP-4) and cathepsin G at a concentration of 1 mM. AP-N inhibitor is non-cytotoxic to U937 cells at a concentration of 100 μM.

  • Target

    Others, Aminopeptidase

  • Related Pathways

    Metabolism, Others

  • CAS Number

    596042

  • Molecular Formula

    C17H10N2O8

  • Molecular Weight

    370.27

  • SMILES

    N(=O)(=O)C1=C(OC=2C(C1=O)=CC=CC2CC(O)=O)C3=C(N(=O)=O)C=CC=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound