Aminopterin sodium - CAS 58602-66-7

Aminopterin sodium is an antineoplastic agent with immunosuppressive properties. Aminopterin works as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase. Its binding affinity for dihydrofolate reductase effectively blocks tetrahydrofolate synthesis.

Others, Antifolate

Others, Cell Cycle/Checkpoint

58529

C19H20N8NaO5

463.41

[Na].Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2n1

-20°C

Ice Packs

Small Compound