Amodiaquine hydrochloride - CAS 69-44-3

Amodiaquine dihydrochloride (Amodiaquin dihydrochloride), a member of the 4-aminoquinoline class, is an antimalarial agent that also acts as a potent oral histamine N-methyltransferase inhibitor with a K i value of 18.6 nM. Additionally, it functions as a Nurr1 agonist, targeting the Nurr1-LBD (ligand binding domain) with an EC 50 of approximately 20 μM, demonstrating anti-inflammatory effects [1] [2] [3] [4] [5].

Others, NR4A, Parasite, Histone Methyltransferase

Chromatin/Epigenetic, Endocrinology/Hormones, Others, Microbiology/Virology

22

C20H24Cl3N3O

428.78

CCN(CC)CC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O.Cl.Cl

-20°C

Ice Packs

Small Compound