AMPK-α1β1γ1 activator 1 - CAS 1943510-86-8

AMPK-α1β1γ1 activator 1 (M1), an acyl glucuronide metabolite derived from an Indole-3-carboxylic Acid-based AMPK activator, selectively activates the β1 isoforms of human AMPK with an EC50 of 38.1 nM through direct binding to the human AMPK α1β1γ1 isoform; it is utilized in diabetic nephropathy research [1].

AMPK

Chromatin/Epigenetic, PI3K/Akt/mTOR signaling

1943510-86-8

C25H24ClNO9

517.91

C(O[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O)(=O)C=2C=3C(=CC(Cl)=C(C3)C4=CC=C(C=C4)C5(O)CCC5)NC2

-20°C

Ice Packs

Small Compound