AMPK activator 11 - CAS 2948304-00-3

AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-activated protein kinase (AMPK) and enhancement of oxidative phosphorylation (OXPHOS) (mitochondrial metabolism) . This compound demonstrates particular efficacy in inhibiting RKO xenograft growth, rendering it useful for anti-tumor and metabolic disease research [1].

AMPK, OXPHOS, Mitochondrial Metabolism

Apoptosis, Metabolism, Chromatin/Epigenetic, PI3K/Akt/mTOR signaling

2948304-00-3

C25H20N4O2

408.45

C(=O)C1=C(NC=2C1=CC=CC2)C=3N=C(NCCC4=CC=C(O)C=C4)C5=C(N3)C=CC=C5

-20°C

Ice Packs

Small Compound