Amsacrine gluconate - CAS 80277-07-2

Amsacrine gluconate is an aminoacridine derivative with potential antineoplastic activity. Although its mechanism of action is incompletely defined, amsacrine may intercalate into DNA and inhibit topoisomerase II, resulting in DNA double-strand breaks, arrest of the S/G2 phase of the cell cycle, and cell death.

Others, Autophagy, Topoisomerase

Others, DNA Damage/DNA Repair, Autophagy

80277-07-2

C27H31N3O10S

589.62

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.COc1cc(NS(C)(=O)=O)ccc1Nc1c2ccccc2nc2ccccc12

-20°C

Ice Packs

Small Compound