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Amsilarotene - CAS 125973-56-0

Amsilarotene - CAS 125973-56-0

MF-0019501-01

$36.91 USD
$36.91 USD
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Product Details

  • Bioactivity

    Amsilarotene (TAC101) inhibits the phosphorylation of retinoblastoma gene product (RB) and increases the presence of 2 cyclin-dependent kinases (CDK) inhibitors resulting in cell cycle arrest. This agent also causes a cytotoxic decline in the thymidylate synthase and cyclin A expression.

  • Target

    Apoptosis, Retinoid Receptor, CDK

  • Related Pathways

    Cell Cycle/Checkpoint, Metabolism, Apoptosis

  • CAS Number

    125917

  • Purity

    0.9927

  • Molecular Formula

    C20H27NO3Si2

  • Molecular Weight

    385.6

  • SMILES

    C[Si](C)(C)c1cc(cc(c1)[Si](C)(C)C)C(=O)Nc1ccc(cc1)C(O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound