Amuvatinib hydrochloride - CAS 1055986-67-8

Amuvatinib hydrochloride (MP470 hydrochloride) is an orally administered multi-targeted tyrosine kinase inhibitor effective against mutant forms of c-Kit, PDGFRα, Flt3, c-Met, and c-Ret, and it suppresses DNA repair by inhibiting the RAD51 protein, contributing to its antineoplastic activity[1][2][3][4].

Others, c-Kit, PDGFR, DNA/RNA Synthesis, c-Met/HGFR, FLT, c-RET

DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Angiogenesis, Apoptosis, Others, Tyrosine Kinase/Adaptors

1055911

C23H22ClN5O3S

483.97

Cl.S=C(NCc1ccc2OCOc2c1)N1CCN(CC1)c1ncnc2c3ccccc3oc12

-20°C

Ice Packs

Small Compound