AMXI-5001 - CAS 2170491-77-5

AMXI-5001 is a potent, orally active inhibitor of PARP1/2 and microtubule aggregation. AMXI-5001 shows selective anti-tumor cytotoxicity against a wide range of human cancer cells with IC50s well below those of existing clinical PARP1/2 inhibitors and induces complete regression of established tumors, including very large ones.

Others, Microtubule Associated

Cytoskeletal Signaling, Others

2170409

C25H20FN5O3

457.46

CCOC(=O)Nc1nc2ccc(cc2[nH]1)-c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F

-20°C

Ice Packs

Small Compound