Amyloid-β-IN-2 - CAS 1603833-55-1

Amyloid-β-IN-2 (Compound EX.112) is a selective inhibitor of γ-secretase. In H4 cells, it demonstrates inhibitory activity on Aβ42 secretion, with an EC50 value of 226 nM. Amyloid-β-IN-2 holds potential for research in Alzheimer's disease (AD) and diseases associated with Aβ deposition.

Beta Amyloid, Gamma-secretase

Neuroscience, Stem Cells, Proteases/Proteasome

1603777

C22H21F2N3O2

397.42

C(NC1=CC(F)=CC(F)=C1)(=O)C2=CC=3C(N2)=CC=C(C3)[C@@H]4CN(C(C)=O)CCC4

-20°C

Ice Packs

Small Compound