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Anacetrapib - CAS 875446-37-0

Anacetrapib - CAS 875446-37-0

SKU:MF-0019980-01

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  • Bioactivity

    Anacetrapib (MK-0859) (MK0859) is an effective, specific, reversible rhCETP and mutant CETP (C13S) inhibitor (IC50: 7.9 nM and 11.8 nM) . Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL thereby, producing an increase in serum HDL-cholesterol levels and a decrease in serum LDL-cholesterol levels.

  • Target

    Others, CETP

  • Related Pathways

    Others, Metabolism

  • CAS Number

    875409

  • Purity

    0.9987

  • Molecular Formula

    C30H25F10NO3

  • Molecular Weight

    637.51

  • SMILES

    COc1cc(F)c(cc1-c1ccc(cc1CN1[C@@H](C)[C@H](OC1=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(F)(F)F)C(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound