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Anagyrine hydrochloride - CAS 74195-83-8
Anagyrine hydrochloride - CAS 74195-83-8
SKU:MF-0065793-01
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Product Details
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Bioactivity
Anagyrine hydrochloride ((-) -Anagyrine hydrochloride), a quinolizidine alkaloid discovered in Lupinus albus, interacts with both muscarinic and nicotinic acetylcholine receptors, demonstrating IC50 values of 132 and 2096 μM, respectively. This compound is recognized for its potent and direct ability to desensitize nAChR without the need for metabolic activation [1] [2] [3].
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Target
AChR, Others
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Related Pathways
Others, Neuroscience
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CAS Number
74104
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Molecular Formula
C15H21ClN2O
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Molecular Weight
280.79
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SMILES
Cl.[H][C@@]12CN3CCCC[C@]3([H])[C@@]([H])(Cn3c1cccc3=O)C2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product