Anbenitamab - CAS 2367012-88-0

Anbenitamab (KN-026) is a bispecific antibody targeting extracellular domains II and IV of human HER2, blocking both ligand-dependent and independent signaling pathways. Its IgG1 Fc fragment activates FcRγIIIa, triggering strong antibody-dependent cell-mediated cytotoxicity (ADCC) and suppressing tumor cell growth. Anbenitamab shows promise for research in HER2-positive metastatic breast cancer (MBC) [1][2].

EGFR

Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis

2366924

-20°C

Ice Packs

Inhibitory Antibodies