And1 degrader 1 - CAS 3029132-46-2

And1 degrader 1 (Compound A15) is a degrader of acidic nucleoplasmic DNA-binding protein 1 (And1) that notably induces degradation of And1 in NSCLC cells. When combined with Olaparib (1 μM), And1 degrader 1 at a concentration of 5 μM effectively inhibits proliferation in A549 and H460 cells. This compound is applicable in cancer research studies.

Others, DNA/RNA Synthesis

Others, DNA Damage/DNA Repair, Cell Cycle/Checkpoint

3029084

C26H27Cl2N3O

468.42

N(CC1=CC(/C=C/C2=CC(Cl)=C(Cl)C=C2)=CC=C1O)C3=CC=C(C=C3)N4CCN(C)CC4

-20°C

Ice Packs

Small Compound