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Androgen receptor antagonist 4 - CAS 354815-43-3
Androgen receptor antagonist 4 - CAS 354815-43-3
SKU:MF-0065826-01
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$1,927.85 USD
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$1,927.85 USD
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Product Details
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Bioactivity
Androgen receptor antagonist 4 (Compound AT2) exhibits anticancer activities by potently antagonizing AR transcriptional activity, inhibiting downstream AR target genes, and blocking DHT-induced nuclear translocation of AR. It is an antagonist of the androgen receptor (AR) with an IC50 of 0.15 μM [1].
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Target
Others, Androgen Receptor
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Related Pathways
Endocrinology/Hormones, Others
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CAS Number
354769
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Molecular Formula
C22H18ClN
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Molecular Weight
331.84
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SMILES
ClC1=CC=C(C2C3C(C=4C=5C(C=CC4N2)=CC=CC5)C=CC3)C=C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound