Androgen receptor-IN-6 - CAS 3016437-05-8

Androgen receptor-IN-6 (compound 16) is an orally active and potent inhibitor of the androgen receptor (IC50=0.12 μMin vitro), targeting its disordered N-terminal domain (NTD) . It demonstrates good permeability in Caco2 cell membranes and exhibits an oral bioavailability (F/%) of 16% in male CD-1 mice.

Androgen Receptor

Endocrinology/Hormones

3016437-05-8

C16H15N3OS

297.38

O=C(N)C1=CC=C(SC)C(=C1)C2=CC=C3C(C=NN3C)=C2

-20°C

Ice Packs

Small Compound