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Annamycin - CAS 92689-49-1
Annamycin - CAS 92689-49-1
SKU:MF-0066002-01
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Product Details
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Bioactivity
Annamycin is a semi-synthetic doxorubicin analogue annamycin with antineoplastic activity. Annamycin intercalates into DNA and inhibits topoisomerase II, resulting in the inhibition of DNA replication and repair and RNA and protein synthesis. This agent circumvents multidrug-resistance (MDR) transporters, including P-glycoprotein (P-gp) .
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Target
Others, Antibiotic
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Related Pathways
Others, Microbiology/Virology
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CAS Number
92639
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Molecular Formula
C26H25IO11
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Molecular Weight
640.37
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SMILES
OC=1C2=C([C@@H](O[C@H]3[C@H](I)[C@H](O)[C@@H](O)[C@H](C)O3)C[C@@](C(CO)=O)(O)C2)C(O)=C4C1C(=O)C=5C(C4=O)=CC=CC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound