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ANO1-IN-4 - CAS 2098490-06-1
ANO1-IN-4 - CAS 2098490-06-1
SKU:MF-0062874-01
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Product Details
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Bioactivity
ANO1-IN-4 (Compound 10bm) is a reversible inhibitor of the calcium-activated chloride channel transmembrane protein 16A (TMEM16A, also known as ANO1), with an IC50 of 0.030 μM. It demonstrates good metabolic stability in rat liver microsomes and can inhibit spontaneous contractions in isolated mouse ileum.
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Target
Chloride channel
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Related Pathways
Membrane transporter/Ion channel
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CAS Number
2098490-06-1
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Molecular Formula
C19H19BrF2N2O2S
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Molecular Weight
457.33
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SMILES
O=C(NC=1C=CC=CC1C)C2=C(SC3=C2CCCCC3)NC(=O)C(F)(F)Br
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound