Antcin B - CAS 163597-25-9

Antcin B is an inhibitor of SARS-CoV-2 3-chymotrypsin-like protease (3CL Pro) . It interacts with several crucial amino acid residues of 3CL Pro, including Leu141, Asn142, Glu166, and His163, through hydrogen bonding, salt bridges, and hydrophobic interactions, thereby inhibiting its activity. This inhibition blocks the cleavage of viral polyproteins and suppresses the replication of the SARS-CoV-2 virus within host cells. Antcin B shows potential for research in the context of COVID-19.

SARS-CoV, Virus Protease

Microbiology/Virology

163597-25-9

C29H40O5

468.625

C[C@@]12C3=C([C@]4([C@](C)(CC3=O)[C@@]([C@@H](CCC(C(C(O)=O)C)=C)C)(CC4)[H])[H])C(=O)C[C@]1([C@H](C)C(=O)CC2)[H]

-20°C

Ice Packs

Natural Product