Anti-inflammatory agent 102 - CAS 3053104-47-2

Anti-inflammatory agent 102 (Compound 11a) is an orally effective anti-inflammatory compound. It exerts its effects by inhibiting the activation of the ASK1/p38 MAPKs/NF-κB signaling pathway. This agent displays significant anti-inflammatory activity by suppressing the release of NO, ROS, and inflammatory cytokines such as IL-6, TNF-α, and IL-1β. Anti-inflammatory agent 102 is applicable in research concerning inflammatory diseases, including ulcerative colitis (UC) .

MAP3K, MAPK, NF-κB, p38 MAPK, Reactive Oxygen Species, Interleukin, NO Synthase

Immunology/Inflammation, NF-κB, MAPK, Metabolism

3053055

C16H16ClN3O3

333.77

O=C1N(C2=NC=CC=C2)CCN1C3=CC(Cl)=C(OC)C=C3OC

-20°C

Ice Packs

Small Compound