Anti-inflammatory agent 104 - CAS 382630-23-1

Anti-inflammatory agent 104 (Compound 26) is an anti-inflammatory compound. It inhibits TNF-α synthesis and release in the U937 human macrophage cell line with an IC50 of 0.024 nM. Additionally, Anti-inflammatory agent 104 reduces eosinophil levels in rat lungs by 63%.

TNF

Apoptosis

382606

C28H32ClFO6S

551.07

O(C(=O)C1=C(C)C=CS1)[C@@]2(C(OC)=O)[C@]3(C)[C@@](C[C@H]2C)([C@]4([C@](Cl)([C@@H](O)C3)[C@]5(C)C([C@@H](F)C4)=CC(=O)C=C5)[H])[H]

-20°C

Ice Packs

Small Compound