Anti-inflammatory agent 105 - CAS 382630-14-0

Anti-inflammatory agent 105 (Compound 12) is an anti-inflammatory compound. It inhibits the synthesis and release of TNF-α in the human macrophage cell line U937, with an IC50 of 0.124 nM.

TNF

Apoptosis

382616

C27H30ClFO7

520.97

O(C(=O)C1=CC=CO1)[C@@]2(C(OC)=O)[C@]3(C)[C@@](C[C@H]2C)([C@]4([C@](Cl)([C@@H](O)C3)[C@]5(C)C([C@@H](F)C4)=CC(=O)C=C5)[H])[H]

-20°C

Ice Packs

Small Compound