Anti-inflammatory agent 21 - CAS 2408836-40-6

Anti-inflammatory agent 21 (compound 9o) is a low cytotoxic, orally active anti-inflammatory agent that targets NO (IC50: 0.76 μM) . It accumulates ROS and inhibits the NF-κB/MAPK signaling pathway to exert anti-inflammatory effects, showing beneficial effects on cartilage destruction and inflammatory cell infiltration in a rat model of arthritis.

Reactive Oxygen Species, NF-κB, Others, NO Synthase

Immunology/Inflammation, Metabolism, NF-κB, Others

2408790

C24H21FO6

424.42

C(O)(C1C=2C(=C(OC)C=C(OC)C2)C(=O)O1)C3=CC=C(OCC4=CC=C(F)C=C4)C=C3

-20°C

Ice Packs

Small Compound