Anti-inflammatory agent 41 - CAS 2896204-90-1

The anti-inflammatory agent 41 (13a) markedly inhibits lipopolysaccharide (LPS) -induced expression of the proinflammatory cytokines IL-6 and TNF-α in J774A.1, THP-1, and LX-2 cells, while also preventing the activation of the NF-κB pathway [1].

Interleukin, NF-κB, TNF

NF-κB, Immunology/Inflammation, Apoptosis

2896204-90-1

C33H25N3O5

543.57

C(NC1=CC=C(OC=2C3=C(C=C(OC)C(OC)=C3)N=CC2)C=C1)(=O)C4=CN(C=5C(C4=O)=CC=CC5)C6=CC=CC=C6

-20°C

Ice Packs

Small Compound