Anti-inflammatory agent 65 - CAS 3035442-58-8

Anti-inflammatory agent 65 (compound 29), a Hederagonic acid derivative, exhibits potent activity by inhibiting nitric oxide (NO) release, nuclear translocation of IRF3 and p65, and disrupting the STING/IRF3/NF-κB signaling pathway, thus attenuating the inflammatory response [1].

STING, NO Synthase

Immunology/Inflammation

3035442-58-8

C49H71NO6S2

834.22

O=C([C@]1([C@@]2([H])CC(C)(C)CC1)CC[C@]3(C)C2=CC[C@@]([C@](CCC([C@]4(COC(CCCNC(CCCC[C@H]5SSCC5)=O)=O)C)=O)(C)[C@@]4([H])CC6)([H])[C@]36C)OCC7=CC=CC=C7

-20°C

Ice Packs

Small Compound