Anti-MRSA agent 14 - CAS 3050586-22-3

Anti-MRSA agent 14 (Compound C17) exhibits antibacterial activity against MRSA and in a MRSA-infected mouse skin model. It demonstrates greater potential against MRSA compared to Norfloxacin. Anti-MRSA agent 14 disrupts cell membranes and inhibits metabolism. Its antibacterial MIC values against S. aureus ATCC 6538, S. aureus ATCC 29213, S. epidermidis ATCC 12228, and MRSA are 1, 2, 2, and 1 μM, respectively.

Antibacterial

Microbiology/Virology

3050561

C43H53ClN2O5S

745.41

C(NS(=O)(=O)C1=CC=C(Cl)C=C1)(=O)[C@]23[C@](C=4[C@@](C)(CC2)[C@@]5(C)[C@](CC4)([C@]6(C)[C@@](CC5)(C(C)(C)C7=C(C6)C=8C(N7)=C(C(O)=O)C=CC8)[H])[H])(CC(C)(C)CC3)[H]

-20°C

Ice Packs

Small Compound