Anti-osteoporosis agent-11 - CAS 2869099-50-1

Anti-osteoporosis agent-11 (compound 3k) is an anti-osteoporosis compound targeting osteoclasts. It exhibits its most prominent effect by inhibiting osteoclast differentiation, with an IC50 value of 0.36 μM. Additionally, Anti-osteoporosis agent-11 suppresses osteoclast formation, bone resorption, and the expression of osteoclast-specific genes by blocking the RANKL-induced mitogen-activated protein kinase (MAPK) and NF-κB signaling pathways.

NF-κB, p38 MAPK, RANKL/RANK

NF-κB, MAPK

2869048

C23H17NO2Se2

497.31

O=C1C([Se]C=2C=CC=CC2)=C([Se]C=3C=CC=CC3)C(=O)N1CC=4C=CC=CC4

-20°C

Ice Packs

Small Compound