Anti-TNBC agent-10 - CAS 2923722-02-3

Anti-TNBC agent-10 is an agent targeting triple-negative breast cancer (TNBC) . It demonstrates potent anti-TNBC activity against BT549 cells with an IC50 of 0.018 μM and remains active in MDA-MB-231 cells with an IC50 of 4.16 μM. In mice with subcutaneous MDA-MB-231 TNBC xenografts, it shows significant antitumor efficacy. Anti-TNBC agent-10 is applicable in TNBC studies.

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2923722-02-3

C11H11F4N5O3

337.23

F[C@@H]1[C@H](N2C=3C(N=C2)=C(N)N=C(C(F)(F)F)N3)O[C@H](CO)[C@H]1O

-20°C

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Small Compound