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Antiangiogenic agent 7 - CAS 2527888-07-7

Antiangiogenic agent 7 - CAS 2527888-07-7

SKU:MF-0110818-01

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  • Bioactivity

    Antiangiogenic agent 7 (Compound 1) induces apoptosis, elevates Reactive Oxygen Species (Reactive Oxygen Species), and inhibits the intracellular enzyme thioredoxin reductase. It exhibits anticancer activity with IC50 values ranging from 0.08 to 3.5 μM against cervical cancer cells (HeLa), prostate cancer cells (PC-3), and non-small cell lung cancer cells (A549) . Additionally, Antiangiogenic agent 7 suppresses tumor growth in a mouse xenograft model.

  • Target

    Apoptosis, Reactive Oxygen Species

  • Related Pathways

    Apoptosis, Metabolism, NF-κB, Immunology/Inflammation

  • CAS Number

    2527888-07-7

  • Molecular Formula

    C24H26AuN3P2S

  • Molecular Weight

    647.46

  • SMILES

    S=P(C=1C=CC=CC1)(C=2C=CC=CC2)C=3C=CC=C[C-]3[Au+][P]45CN6CN(CN(C6)C4)C5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound