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Antiangiogenic agent 7 - CAS 2527888-07-7
Antiangiogenic agent 7 - CAS 2527888-07-7
SKU:MF-0110818-01
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Product Details
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Bioactivity
Antiangiogenic agent 7 (Compound 1) induces apoptosis, elevates Reactive Oxygen Species (Reactive Oxygen Species), and inhibits the intracellular enzyme thioredoxin reductase. It exhibits anticancer activity with IC50 values ranging from 0.08 to 3.5 μM against cervical cancer cells (HeLa), prostate cancer cells (PC-3), and non-small cell lung cancer cells (A549) . Additionally, Antiangiogenic agent 7 suppresses tumor growth in a mouse xenograft model.
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Target
Apoptosis, Reactive Oxygen Species
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Related Pathways
Apoptosis, Metabolism, NF-κB, Immunology/Inflammation
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CAS Number
2527888-07-7
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Molecular Formula
C24H26AuN3P2S
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Molecular Weight
647.46
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SMILES
S=P(C=1C=CC=CC1)(C=2C=CC=CC2)C=3C=CC=C[C-]3[Au+][P]45CN6CN(CN(C6)C4)C5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound