Antibiotic DC 81 - CAS 81307-24-6

Antibiotic DC 81, a pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumor antibiotic produced by Streptomyces species, acts as a potent inhibitor of nucleic acid synthesis. It specifically recognizes and binds to certain DNA sequences, forming a labile covalent adduct [1] [2].

Apoptosis, Others, DNA/RNA Synthesis, Antibiotic

Others, Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Microbiology/Virology, Apoptosis

81277

C13H14N2O3

246.26

[H][C@@]12CCCN1C(=O)c1cc(OC)c(O)cc1N=C2

-20°C

Ice Packs

Small Compound