Anticancer agent 128 - CAS 2941243-62-3

Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, showing IC50 values of 24.9 nM, 19.3 nM, and 10.3 nM, respectively [1].

IAP

Apoptosis

2941178

C26H38N4O4

470.6

N(C(=O)[C@H]1N(C([C@@H](NC([C@@H](NC)C)=O)C2CCCCC2)=O)CCC1)[C@H]3C=4C(CC3)=C(O)C=CC4

-20°C

Ice Packs

Small Compound