Anticancer agent 164 - CAS 2235393-30-1

CML-IN-1, also known as compound 7 and compound 4, is a potent anticancer agent that demonstrates a strong induced-apoptosis effect in the human chronic myeloid leukemia (CML) cell line K562. It diminishes protein phosphorylation within the PI3K/Akt signaling pathway to exert its effects and suppresses cell proliferation through the inhibition of the MEK/ERK signaling pathway in colorectal cancer [1] [2].

Apoptosis, MEK, PI3K

PI3K/Akt/mTOR signaling, Apoptosis, MAPK

2235362

C21H23F3N8O2S2

540.58

S(C=1SC(NC(NC2=CC=C(C(F)(F)F)C=C2)=O)=NN1)C=3C=C(NCCCN4CCOCC4)N=CN3

-20°C

Ice Packs

Small Compound