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Anticancer agent 183 - CAS 3018960-58-9

Anticancer agent 183 - CAS 3018960-58-9

MF-0120312-01

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Product Details

  • Bioactivity

    Anticancer agent 183 (compound 4h) exhibits potent inhibition of matrix metalloproteinase-9 (MMP-9), reducing its viability by more than 75% at a concentration of 100 μg/mL. Additionally, it demonstrates significant anticancer activity, with an IC50 value of <0.14 μM against the A549 cell line and induces apoptotic [1] processes.

  • Target

    Apoptosis, MMP

  • Related Pathways

    Proteases/Proteasome, Apoptosis

  • CAS Number

    3018960-58-9

  • Molecular Formula

    C19H18N4O4S

  • Molecular Weight

    398.44

  • SMILES

    O=C(NC=1C=CC=CC1OCC2=NN=C(O2)SCC(=O)NC=3C=CC=CC3)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound