Anticancer agent 260 - CAS 345994-70-9

Anticanceragent 260 (Compound 3g/4d) is an orally effective anticancer agent that inhibits the proliferation of cancer cells HCT-116, MIA-PaCa2, and MDA-MB231, with IC50 values of 98.7, 81.0, and 77.2 μg/mL, respectively. It also promotes ulcer formation and lipid peroxidation, and exhibits anti-inflammatory and analgesic activities.

Reactive Oxygen Species

Metabolism, NF-κB, Immunology/Inflammation

345915

C14H11N3O

237.26

N=1N=C(OC1C=2C=CN=CC2)C=3C=CC=CC3C

-20°C

Ice Packs

Small Compound