Anticancer agent 56 - CAS 2241915-59-1

Anticancer agent 56 (compound 4d) is a powerful anti-cancer compound with favorable drug-like properties, showing significant anticancer activity against multiple cancer cell lines with an IC50 value of less than 3 μM. It exerts its effects by causing cell cycle arrest at the G2/M phase and activating the mitochondrial apoptosis pathway, inducing the accumulation of reactive oxygen species (ROS), upregulating BAX, downregulating Bcl-2, and triggering the activation of caspases 3, 7, and 9 [1].

Reactive Oxygen Species, Caspase, Apoptosis, Bcl-2 Family, Others

Proteases/Proteasome, Immunology/Inflammation, NF-κB, Others, Apoptosis, Metabolism

2241855

C20H18ClN3O3

383.83

CC=1N(N=NC1C(/C=C/C2=CC(OC)=C(OC)C=C2)=O)C3=CC=C(Cl)C=C3

-20°C

Ice Packs

Small Compound