Anticancer agent 63 - CAS 2529657-32-5

Anticancer agent 63 (compound 3h) exhibits significant cytotoxic activity against multiple cancer cell lines, including SW480, HeLa, A549, and MCF-7, with IC50 values of 4.9, 11.5, 9.4, and 3.4 μM, respectively, after 24 hours of treatment. It induces apoptosis in MCF-7 cells by down-regulating Bcl-2 expression and up-regulating IL-2 and Caspase-3 expression, and also demonstrates antioxidative properties [1].

Caspase, Apoptosis, Bcl-2 Family, Others

Proteases/Proteasome, Others, Apoptosis

2529620

C17H24F3NOSe

394.33

C(C(NCCC[Se]C(F)(F)F)=O)(C)C1=CC=C(CC(C)C)C=C1

-20°C

Ice Packs

Small Compound